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英文名稱： UTP4 Antigen (Recombinant Protein)
別 名： UTP4, small subunit processome component; NAIC; CIRH1A; CIRHIN; TEX292
儲 存： 冷凍（-20℃）
相關類別： 抗原
概述
|
Fusion protein corresponding to a region derived from 487-686 amino acids of human UTP4 |
|
Full name: |
UTP4, small subunit processome component |
|
Synonyms: |
NAIC; CIRH1A; CIRHIN; TEX292 |
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Swissprot: |
Q969X6 |
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Gene Accession: |
BC009348 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants. |
